Host-Pathogen Interactions in Gram-Positive Bacterial Pneumonia

Gram-positive phage-host interactions

Bacteriophage research has seen many peaks and troughs over the past century ascending with phage therapy and application in the early 1900’s; a research peak which was largely overshadowed by the dawning of the antibiotic era, and which has now deservedly regained attention as an approach against the problematic rise in antibiotic-resistant pathogenic bacteria. Following this initial scientifi...

HOST-PATHOGEN INTERACTIONS IN GRAM-POSITIVE BACTERIOSIS IN FARMED TURBOT (Scophthalmus maximus)

Bacterial Lipoproteins Diverse Role in Host-Pathogen Interactions

Introduction In the recent years, primarily due to the advances in genome sequencing of bacteria, an increased number of lipoproteins have been predicted in the various strains of bacteria. Bacterial lipoproteins are critical for the survival of both the Grampositive and Gram-negative bacteria. Bacteria are found on the surface of host or within the body as commensals or as pathogenic organisms...

Bacterial serine/threonine protein kinases in host-pathogen interactions.

In bacterial pathogenesis, monitoring and adapting to the dynamically changing environment in the host and an ability to disrupt host immune responses are critical. The virulence determinants of pathogenic bacteria include the sensor/signaling proteins of the serine/threonine protein kinase (STPK) family that have a dual role of sensing the environment and subverting specific host defense proce...

Bacterial endophthalmitis: therapeutic challenges and host-pathogen interactions.

Endophthalmitis is an infection of the posterior segment of the eye that frequently results in loss of vision. This devastating result occurs despite prompt and often aggressive therapeutic and surgical intervention. Over the past decade, research has centered on determining the bacterial and host factors involved in this potentially blinding disease. The initial focus on the bacterial factors ...